For precision cancer medicine, we have been developing an Integrated Cancer Clinical Database System(ICDB) with AI, which automatically collects and stores structured labeled data, such as clinical data in text format, pathological data, genome and liquid biopsy data, from the Electronic Health Record(EHR). The ICDB is an independent and vendor-neutral database system which can connect to any EHR. Oncologists can use AI powered ICDB to recommend and share the most suitable cancer treatment for each patient. During shared decision-making process AI communication system supports patients and physicians for precise approach and communication, regarding patient personality and level of understanding. An AI communication robot supports us during cancer pharmaceutical treatments as an electric patient reported outcome. Cancer information is growing at an accelerated rate, which exceeds the human ability to organize, memorize, and appropriately use. Therefore, AI assistance in Cancer Medical Development is essential. Positive and active application of AI will enable compensation for uneven distribution of experts and labor shortages of healthcare professionals due to an aging society. We are consistently developing future cancer precision treatment with AI assistance.