Intraplantar injection of carrageenan into the hind paw of rodents is used to induce experimental inflammatory symptoms, including nociceptive behaviour. The unilateral injection of carrageenan into a hind paw to provoke inflammation was reported to enhance nociceptive sensitivity in the contralateral paw in rats. In order to provide balanced stimulation to the both sides, carrageenan should be injected bilaterally into the hind paws. In the present study we analysed the effects of systemic administration of meloxicam, a non-steroidal anti-inflammatory drug, or morphine on paw withdrawal and threshold forces in response to tactile stimuli in rats with bilateral intraplantar injections of carrageenan into hind paws. For comparison, effects of these analgesic drugs were also analysed in rats with a bilateral sciatic nerve ligation to produce neuropathic pain. In both carrageenan-treated and sciatic nerve-ligated rats, the paw withdrawal responses and threshold forces in response to tactile stimuli were increased and decreased, respectively. These nociceptive behaviours of carrageenan-treated rats were each inhibited by meloxicam and morphine. Morphine, but not meloxicam, inhibited the behavioural changes in sciatic nerve-ligated rats. The inhibitory effect of morphine in carrageenan-treated rats was much larger than that in nerve-ligated rats. These results suggest that rats with bilateral intraplantar injection of carrageenan into hind paws can be considered an animal model of inflammatory pain.