One of the educational goals for pathology is to understand "Defining the etiology and pathogenesis of the disease." On the other hand, understanding the rationality of pharmaceutical treatments based on the etiology or the pathogenesis has been considered beyond pathology education, despite the recent rapid progress in understanding the diseases at the molecular level.
As molecular pathological diagnosis provides evidence for determining the use of therapeutic agents that target abnormal molecules, so far as we know, understanding its efficacy must require knowledge to connect pharmacological effects with changes at the molecular cell level. Furthermore, it is not uncommon to point out the presence or absence of adverse drug reactions in clinical practices, clinic-pathological conference, and even in autopsy, where therapeutic effects and pathologic reaction may share the molecular interaction. Therefore, medical education must expand the chance to know the pathophysiology triggered by therapeutic drug use. For these reasons, this paper will demonstrate the necessity of pharmacology and pathology collaboration in medical education and would like to propose and discuss a pharmacological pathology for understanding the rational selections and appropriate effect evaluation of the therapeutic drug.