Although valuable findings are obtained in pharmacological research, the bridge between basic and clinical research is a barrier, since clinical applications are limited. Therefore, the development of a new research method is required to bridge the knowledge acquired from basic and clinical pharmacological researches. Furthermore, our laboratory realized the association between basic and clinical pharmacological findings utilizing medical big data. Therefore, by using the strategy to develop basic pharmacological experiments from useful findings obtained from clinical pharmacological research via various medical big data, the efficacy and human safety can be accurately predicted and applied to clinical applications.
Several medical information (receipt data) and life science (gene expression data) databases have been developed and maintained, but there are few databases for basic and clinical pharmacological researches. In this symposium, we have demonstrated research examples that connects basic and clinical pharmacological researches by utilizing medical big data and discussed future prospects.